The performers were announced Wednesday for the June 6 awards show held in Nashville, Tennessee, and airing on CMT.
Clarkson is making her CMT Awards show debut with a performance of the classic rock song "American Woman." The song will be the theme song for a new TV show of the same name on Paramount Network starring Alicia Silverstone and Mena Suvari.
Stapleton and Shelton are both nominated for video of the year, while Carrie Underwood, Florida Georgia Line and Jason Aldean are tied for the most nominations with four each.
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