Howard Stern on Tuesday announced the invitation-only event for SiriusXM subscribers during his show on the satellite music service.
The company says U2 will play songs from its "Songs of Experience" album along with classics from its career.
Bono calls it a bucket-list moment and says it's "an incredible honor" to play on the same stage in Harlem that has hosted the legends of soul.
SiriusXM subscribers can win tickets to the June 11 performance through an invitation sent by email.
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