Chancellor Mark Nordenberg said Friday that more than 182,000 donors have contributed to the landmark capital campaign.
Officials say the effort has enabled major construction projects at all five Pitt campuses, plus supported educational and research initiatives.
Pitt began the "Building Our Future Together" campaign 12 years ago with the goal of raising $500 million. After reaching that milestone in 2002, the target was doubled to $1 billion. In 2007, the goal was doubled again to $2 billion.
Pitt officials say the university is one of 10 nationwide pursuing $2 billion campaigns.
Pitt is a state-related school serving about 29,000 students on its main campus and nearly 7,000 more at regional locations.