Police said two trucks and a sport utility vehicle were heading east on Interstate 80 in East Lackawannock Township at about 6:40 p.m. Sunday when they collided.
Police in Mercer County reported that two girls in the SUV were pronounced dead at the scene. Two other female victims, including the 17-year-old driver, were taken to a Pittsburgh hospital.
One tractor-trailer driver was taken to Grove City Medical Center for treatment of unspecified injuries. The other truck driver was uninjured.
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