Areas east of a line from Kittanning to Irwin to Waynesburg could end up with an inch or so on the ground before the snow tapers off, said meteorologist Scott Harbaugh.
Some areas east of Route 119 from Indiana to Uniontown will get 1-3 inches of snow, with the higher amounts being in the mountains.
Channel 11's Courtney Brennan talked to PennDOT crews in Westmoreland County, an area that got some snowfall on Wednesday.
Westmoreland County Hit With Winter Blast
PennDOT planned to have 68 plows on the road in Westmoreland County on Wednesday night.
Plow drivers will spread between 60 and 100 tons of the salt anti-skid mixture on the roads.
The biggest concern for the Pittsburgh area will be wet roads freezing tonight, as temperatures are expected to drop below 32 degrees.
Black ice could be a big issue for the Thursday morning commute, Harbaugh said.