Channel 11's Rick Earle took the list to local leaders to find out what's being done to reduce the number of accidents and deaths.
According to the list created by the Pennsylvania Department of Transportation, there are 377 roadways that are considered high-crash locations across the state. The Pittsburgh area is home to 33 of those sites.
Frankstown Road near Penn Hills is considered one of the most dangerous. During a five-year period, there were 77 accidents and three fatalities on that stretch of road, the report shows.
A man who lives nearby said he's not surprised that the roadway has ranked among the worst in Pennsylvania.
"Not surprised at all. I mean, what I see every day, you would not believe what I've witnessed," said the man who lives along Frankstown Road. "It's going to be another fatality. It's bound to happen. It's just a matter of time."
The man said he has sent letters to city officials asking for speed traps, but so far he has not received a response.
Other roadways that made the list included Fifth Avenue in Pittsburgh. The report shows that there were 131 accidents in a five-year period.
Route 28 in Pittsburgh had 147 accidents in the same amount of time.
The roadway with the highest amount of crashes in the area is Saw Mill Run Boulevard. The list shows that there were 188 crashes within five years.
Drivers who frequently travel Saw Mill Run Boulevard said accidents are something they've become accustomed to seeing.
"I almost got rear-ended like five times," said driver Samantha Meier. "When a big truck comes through I always see cars swerving over."
The report also shows where the most fatalities occurred. Route 28, Route 837 in West Homestead and Liberty Avenue in downtown Pittsburgh each had four within 2003 to 2007.
Five people died in a five-year period on West Liberty Avenue between Pittsburgh and Dormont.
Freeport Road in Natrona was reported as the deadliest, with nine fatalities in five years.
Todd Kravits, a PennDOT engineer said while driver behavior accounts for more than half of the accidents, he also said some engineering or design changes could be needed to improve safety on some of the roads.
Kravits said they are planning changes for Freeport Road.
"We are actually going to narrow those lanes down a bit, which will help us in reducing speed, and it will allow a refuge area for cars that want to make left hand turns at the intersection," said Kravits.
Crews are conducting similar improvements and repaving West Liberty Avenue , according to Kravits.
Kravits said there were more complicated problems on Route 28, where crews interchanges are being constructed and traffic lights are being removed.
"Because of traffic getting backed up, you come around the bend and you don't see it, and we end up with a series of rear-end accidents," Kravits said.